Steve Fuller and
Veronika Lipinska's
The Proactionary Imperative: A Foundation for Transhumanism (Palgrave Macmillan, 2014) debates the concept of transforming human nature, including such thorny topics as humanity's privilege as a species, our capacity to 'play God', the idea that we might treat our genes as a capital investment, eugenics and what it might mean to be 'human' in the context of risky scientific and technological interventions.
John Danaher is a lecturer the National University of Ireland, Galway. He is also the host of the wonderful podcast Philosophical Disquisitions. You can find it here on Apple Podcasts.